Абатацепт и риск сердечно-сосудистых осложнений при ревматоидном артрите: современные данные
https://doi.org/10.14412/1996-7012-2017-4-56-51
Аннотация
Одной из основных причин летальности при ревматоидном артрите (РА) являются сердечно-сосудистые осложнения (ССО) – инфаркт миокарда (ИМ), инсульт и внезапная сердечная смерть, – обусловленные ранним развитием и быстрым прогрессированием атеросклероза сосудов. Показано, что при РА возникновение атеросклероза и его клинических проявлений обусловлено традиционными факторами риска (ТФР) и иммуновоспалительными механизмами, лежащими в основе патогенеза этих заболеваний. Поскольку ключевая роль в развитии атеросклероза и связанных с ним ССО при РА принадлежит хроническому воспалению и аутоиммунным нарушениям, важное место в их профилактике занимает эффективная противовоспалительная терапия. В обзоре представлены современные данные о влиянии абатацепта на общую летальность и ССО, ТФР сердечно-сосудистых заболеваний, клинические и субклинические проявления атеросклероза при РА.
Об авторе
Т. В. Попкова
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», Москва
Россия
Россия
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Рецензия
Для цитирования:
Попкова ТВ. Абатацепт и риск сердечно-сосудистых осложнений при ревматоидном артрите: современные данные. Современная ревматология. 2017;11(4):56-51. https://doi.org/10.14412/1996-7012-2017-4-56-51
For citation:
Popkova TV. Abatacept and cardiovascular risk in rheumatoid arthritis: update. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2017;11(4):56-51. (In Russ.) https://doi.org/10.14412/1996-7012-2017-4-56-51
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