Остеоартрит суставов кисти: диагностика, патогенез, лечение

На ранних стадиях остеоартрит кисти (ОАК) из-за развития синовита напоминает поражение суставов кисти при ревматоидном артрите (РА). Однако локализация синовита при этих  заболеваниях различна: при ОАК в процесс вовлечены дистальные межфаланговые суставы  и суставы большого пальца. При ОАК отрицательны результаты тестов на иммунологические маркеры (антитела к цитруллинированному пептиду), что типично для РА. Различия ОАК и РА  очевидны при рентгенографии и магнитно-резонансной томографии кисти. Изучение  патогенеза остеоартрита (ОА) свидетельствует о роли дисбаланса цитокинового профиля, что  сближает его с РА. Терапия ОАК практически не разработана, имеются лишь отдельные  исследования, посвященные применению базисных противовоспалительных и биологических  препаратов у таких пациентов. Отмечена необходимость создания отечественных рекомендаций по лечению ОАК.

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