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Current possibilities for early diagnosis of systemic lupus erythematosus

https://doi.org/10.14412/1996-7012-2018-3-34-39

Abstract

The review presents the data available in the literature on the use of the lupus band test (LBT) for systemic lupus erythematosus (SLE). LBT is a direct immunofluorescence method used to detect immunoglobulins and complement factors in the dermoepidermal junction of skin biopsy specimens. LBT may be applied as one of the diagnostic tests for early diagnosis of SLE in patients without skin manifestations and in those of incomplete SLE. Like the results of other laboratory tests, those of LBT may be taken into account when establishing a final diagnosis only in conjunction with other clinical, immunological and instrumental data.

About the Authors

V. A. Lila
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation

Viktoria Aleksandrovna Lila

41, Kirochnaya St., Saint Petersburg 191015



V. I. Mazurov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
41, Kirochnaya St., Saint Petersburg 191015


S. V. Lapin
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation
6–8, Lev Tolstoy St., Saint Petersburg 197022


A. V. Mazing
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation
6–8, Lev Tolstoy St., Saint Petersburg 197022


A. N. Moshnikova
Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation
6–8, Lev Tolstoy St., Saint Petersburg 197022


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Review

For citations:


Lila VA, Mazurov VI, Lapin SV, Mazing AV, Moshnikova AN. Current possibilities for early diagnosis of systemic lupus erythematosus. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2018;12(3):34-39. (In Russ.) https://doi.org/10.14412/1996-7012-2018-3-34-39

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ISSN 1996-7012 (Print)
ISSN 2310-158X (Online)