A clinical case of adult-onset Still's disease resistant to therapy with tumor necrosis factor-alpha inhibitors and interleukin-6 inhibitors
https://doi.org/10.14412/1996-7012-2019-1-91-94
Abstract
The basis of the clinical picture of adult-onset Still's disease is a triad of symptoms, includingfever, arthralgia/arthritis, and characteristic rash called «Still rash». The first line of therapy includes glucocorticoids, synthetic disease-modifying anti-rheumatic drugs; biological agents, such as tumor necrosis factor a inhibitors and interleukin-6 and interleukin-1 inhibitors, are used in standard therapy-resistant cases.
About the Authors
R. R. Samigullina
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Rusana Ramilovna Samigullina
41, Kirochnaya St., Saint-Petersburg 191015
E. A. Vasilenko
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
41, Kirochnaya St., Saint-Petersburg 191015
V. I. Mazurov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
41, Kirochnaya St., Saint-Petersburg 191015
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Review
For citations:
Samigullina RR, Vasilenko EA, Mazurov VI. A clinical case of adult-onset Still's disease resistant to therapy with tumor necrosis factor-alpha inhibitors and interleukin-6 inhibitors. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2019;13(1):91-94. (In Russ.) https://doi.org/10.14412/1996-7012-2019-1-91-94
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