Вакцинация при системной красной волчанке: современное состояние проблемы

Вакцинация играет важную роль в профилактике инфекций у пациентов с иммуновоспалительными заболеваниями. При вакцинации пациентов с системной красной волчанкой (СКВ), как и с другими иммуновоспалительными ревматическими заболеваниями, большое значение придается ее безопасности, включая нивелирование рисков основного заболевания или развития новых аутоиммунных феноменов. Многие практикующие врачи продолжают считать аутоиммунные заболевания противопоказанием для вакцинации из-за предполагаемой возможности их обострения и снижения эффективности вакцины на фоне активной иммуносупрессивной терапии.

В лекции представлены современные данные об иммуногенности, эффективности и безопасности вакцин против ряда инфекций, вызываемых вирусами гриппа, гепатита В, Herpes zoster, папилломы человека, COVID-19 и пневмококком, у больных СКВ.

Показано, что преимущества вакцинации у больных СКВ существенно превосходят риск нежелательных явлений или обострений заболевания. В то же время отмечено, что проблема вакцинации таких пациентов требует дальнейшего изучения.

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