Cutaneous necrotizing vasculitis in a patient with rheumatoid arthritis that developed after COVID-19: description of a clinical case
https://doi.org/10.14412/1996-7012-2024-4-89-92
Abstract
The article discusses the pathogenesis and clinical manifestations of cutaneous vasculitis in rheumatoid arthritis (RA) and the role of autoimmune disturbances in the development of micro- and macrovascular thrombosis of the venous and arterial vessels caused by SARS-CoV-2 virus infection.
A clinical case is described in which skin necrosis in the elbow joint area developed in a patient with a long-term course of RA after COVID-19. The process subsided against the background of treatment with an interleukin-6 inhibitor.
About the Authors
R. M. Balabanova
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
L. N. Denisov
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
References
1. Nasonova VA. Rheumatoid arthritis with systemic manifestations – diagnosis and prognosis. Terapevticheskii arkhiv. 1983;55(7): 3-6. (In Russ.).
2. Nasonova VA, Nasonov EL. Vasculitis in rheumatic diseases. In: Vasculitis and vasculopathy. Yaroslavl'; 1999. P. 515-520.
3. Gritsman NN, Akhnazarova VD, Rusakova MS. Features of immunomorphological reactions in tissues in rheumatic diseases. Voprosy revmatizma. 1980;(3):14-17. (In Russ.).
4. Scott DG, Bacon PA. Systemic rheumatoid vasculitis: a clinical and blaboratory study of 50 cases. Medicine (Baltimore). 1981 Jul;60(4): 288-97.
5. Umetova MD. Clinical and immunological characteristics of rheumatoid vasculitis. Autoref. diss. cand. med. sci. Moscow; 1981.
6. Padenska-Lopovok SG, Balabanova RM. Rheumatoid arthritis. In: Handbook of Internal Medicine. Rheumatic diseases. Moscow: Meditsina; 1997. P. 257-294.
7. Chen KR, Toyohara A, Suzuki A, Miyakawa S. Clinical and histopathological spectrum of cutaneous vasculitis in rheumatoid arthritis. Br J Dermatol. 2002 Nov; 147(5): 905-13. doi:10.1046/j.1365-2133.2002.04933.x.
8. Puechai X, Said G, Hiiliquin P, et al. Periferal neuropathy with necrotizing vasculitis in rheumatoid arthritis. A clinico-pathologic and prognostic study of 32 patients. Arthritis Rheum. 1995 Nov;38(11):1618-29. doi: 10.1002/art.1780381114.
9. Balabanova RM. Rheumatoid arthritis with systemic manifestations (clinic, treatment, prognosis). Autoref. diss. doct. med. sci. Moscow; 1990.
10. Bestayev DV, Karateev DE. Skin vasculitis in rheumatoid arthritis patients. Nauchno-prakticheskaya revmatologia. 2014;52(1):91-98. (In Russ.).
11. Belov BS, Aronova ES, Gridneva GI, Nasonov EL. Rheumatoid arthritis and COVID-19: three years later. Nauchno-prakticheskaya revmatologia. 2023;61(4):450-457. (In Russ.).
12. Ciaffi J, Meliconi R, Ruscitti P, et al. Rheumatic manifestations of COVID-19: a systematic review and meta-analysis. BMC Rheumatol. 2020 Oct 28:4:65. doi: 10.1186/s41927-020-00165-0. eCollection 2020.
13. Nasonov EL, Beketova TV, Reshetnyak TM, et al. Coronavirus disease 2019(COVID-19) and immune-mediated inflammatory rheumatic diseases: at the crossroads of thromboinflamation and autoimmunity. Nauchnoprakticheskaya revmatologia. (In Russ.).
14. Connors JM, Levy JH. Tromboinflamation and the hypercoagulability of COVID-19. J Thromb Haemost. 2020 Jul;18(7):1559-1561. doi: 10.1111/jth.14849. Epub 2020 May 26.
15. Becker RC. COVID-19 update: COVID-19 – associated coagulopathy. J Thromb Thrombolysis. 2020 Jul;50(1):54-67. doi: 10.1007/s11239-020-02134-3.
16. Varga Z, Flammer AJ, Steiger P, et al. Endotheliopathy in COVID-19-associated coagulopathy:evidence from a single-centre, cross-sectional study. Lancet Haematol. 2020 Aug;7(8):e575-e582. doi: 10.1016/S2352-3026(20)30216-7. Epub 2020 Jun 30.
17. Dvoryankina EV, Korsunskaya IM, Slavyanskaya TA. Skin manifestations of COVID-19. Vestnik RUDN. Meditsina. 2021;25(1):9-15. (In Russ.).
18. Sollini M, Ciccarelli M, Cecconi V, et al. Vasculitis changes in COVID-19 survivors with persistent symptoms. Eur J Nuclear Med Mol Immaging. 2021 May;48(5);1460-6. doi: 10.1007/s00259-020-05084-3.
19. Abdulganieva DI, Shamsutdinova NG, Gaibaryan AA. COVID-19-associated angiitis: literature review and case report. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2022;16(1):73-76. (In Russ.). doi: 10.14412/1996-7012-2022-1-73-76.
20. Sunderkotter C, Golle L, Pillebont E, Michl C. Pathophysiology and clinical manifestations of immune complex vasculitides. Front Med (Lausanne); 2023 Mar 3;10:1103065. doi:10.3384/fmed.2023.1103065. eCollection 2023
21. Sugino H, Sawada Y, Nakamura M. IGA vasculitis: ethiology treatment, biomarkers and epigenetic changes. Int J Mol Sci. 2021 Jul 14;22(14):7538. doi: 10.3390/ijms22147538.
22. Solomay TV, Semenenko TA, Filatov NN, et al. Reactivation of Epstein–Barr virus infection during COVID-19: epidemiological features. Voprosy virusologii. 2021;(2):152-161. (in Russ.).
23. Kim JYH, Ragusa M, Tortosa F, et al. Viral reactivations and co-infections in COVID 19: a systemic review. BMC Infect Dis. 2023 Apr 26;23(1):259. doi: 10.1186/s12879-023-08117-y.
24. Nodeem A, Suresh K, Awais H, et al. Epstein–Barr virus cоinfection in COVID-19. J Investig Med High Impact Case Rep. 2021 Jan-Dec:9:23247096211040626. doi: 10.1177/23247096211040626.
25. Muhd Besari A, Lim JA, Vellaichamy PT, et al. Stevens–Johnson syndrome as a primery skin manifestation of COVID-19. Postgrad Med J. 2022 Mar;98(e2):e70. doi:10.1136/postgradmedj-2021-140778.
26. Goeijenbier M, van Wissen M, van de Weg C, et al. Viral infections and mechanisms of thrombosis and bleeding. J Med Virol. 2012 Oct;84(10):1680-96. doi: 10.1002/jmv.23354.
27. Nasonov EL, Avdeeva AS. B cell depletion in immune-mediated rheumatic diseases and coronavirus diseas 2019. Nauchno-prakticheskaya revmatologia. 2021;59(4):384-393. (In Russ.).
28. Cavalli G, Colafrancesco S, De Luca G, et al. Cutaneous vasculitis following COVID-19 vaccination. Lancet Rheumatol. 2021 Nov; 3(11):e743-e744. doi: 10.1016/S2665-9913 (21)00309-X. Epub 2021 Sep 30.
29. Larson V, Seidenberg R, Caplan A, et al. Clinical and histopathological spectrum of delayed adverse cutaneous reactions following COVID-19 vaccination. J Cutan Pathol. 2022 Jan;49(1):34-41. doi: 10.1111/cup.14104. Epub 2021 Aug 8.
30. Belov BS, Egorova ON, Tarasova GM, Muravieva NV. Infections and systemic vasculitis. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2022;16(5):75-81. (In Russ.). doi: 10.14412/1996-7012-2022-5-75-81.
Review
For citations:
Balabanova RM, Denisov LN. Cutaneous necrotizing vasculitis in a patient with rheumatoid arthritis that developed after COVID-19: description of a clinical case. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2024;18(4):89-92. (In Russ.) https://doi.org/10.14412/1996-7012-2024-4-89-92
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