ANTISYNTHETASE SYNDROME IS THE MOST SEVERE SUBTYPE OF POLYMYOSITIS/DERMATOMYOSITIS:DESCRIPTION OF CASES
https://doi.org/10.14412/1996-7012-2009-574
Abstract
Polymyositis (PM) and dermatomyositis (DM) are autoimmune skeletal muscle diseases of unknown etiology, which are referred to as systemic connective tissue diseases and united under the common term Tidiopathic inflammatory myopathiesy. The most severe subtype of PM/DM is the antisynthetase syndrome that is characterized by a certain sympathocomplex, including interstitial lung lesion that is one of the most common visceral changes. Of interest are the specific features of the antisynthetase syndrome, its onset, the course and pulmonary manifestations of fibrosing alveolitis, unlike the classical course of PM/DM. Two clinical cases of the antisynthetase syndrome are given.
About the Authors
Olga Alekseyevna AntelavaG M Tarasova
E G Sazhina
Yu A Olyunin
R M Balabanova
E L Nasonov
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Review
For citations:
Antelava OA, Tarasova GM, Sazhina EG, Olyunin YA, Balabanova RM, Nasonov EL. ANTISYNTHETASE SYNDROME IS THE MOST SEVERE SUBTYPE OF POLYMYOSITIS/DERMATOMYOSITIS:DESCRIPTION OF CASES. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2009;3(4):54-58. (In Russ.) https://doi.org/10.14412/1996-7012-2009-574
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