Osteoarthritis of the hands: epidemiology, risk factors, and modern diagnostics
https://doi.org/10.14412/1996-7012-2025-4-13-24
Abstract
Osteoarthritis (OA) is a prevalent rheumatic disease characterized by structural and functional joint abnormalities, leading to significant functional and quality of life impairment. Hand OA ranks second in prevalence after knee OA. This article reviews current data on the epidemiology and risk factors of hand OA, and highlights the new EULAR classification criteria, which incorporate radiographic features of generalized OA, involvement of interphalangeal joints, and OA of the first carpometacarpal joint in patients with pain, discomfort, and/or stiffness. The article also presents findings from the ISKRA study, which demonstrated the efficacy of a bioactive small marine fish concentrate in 2,776 patients with hand OA.
About the Authors
E. A. TaskinaRussian Federation
Elena Alexandrovna Taskina - MD, PhD, Senior Research Fellow, Laboratory of Osteoarthritis, Department of Metabolic Diseases of Bones and Joints,
34A, Kashirskoye Shosse, Moscow 115522
A. M. Lila
Russian Federation
34A, Kashirskoye Shosse, Moscow 115522;
2/1, Barrikadnaya Street, Build. 1, Moscow 125993
N. G. Kashevarova
Russian Federation
34A, Kashirskoye Shosse, Moscow 115522
L. I. Alexeeva
Russian Federation
34A, Kashirskoye Shosse, Moscow 115522;
2/1, Barrikadnaya Street, Build. 1, Moscow 125993
A. R. Khalmetova
Russian Federation
34A, Kashirskoye Shosse, Moscow 115522
References
1. Xie X, Zhang K, Li Y, et al. Global, regional, and national burden of osteoarthritis from 1990 to 2021 and projections to 2035: A cross sectional study for the Global Burden of Disease Study 2021. PLoS One. 2025 May 27; 20(5):e0324296. doi: 10.1371/journal.pone.0324296. eCollection 2025.
2. Dieleman JL, Cao J, Chapin A, et al. US Health Care Spending by Payer and Health Condition, 1996–2016. JAMA. 2020 Mar 3;323(9):863-884. doi: 10.1001/jama.2020.0734.
3. Steinmetz JD, Culbreth GT, Haile LM, et al. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023 Aug 21;5(9):e508-e522. doi: 10.1016/S2665-9913(23)00163-7. eCollection 2023 Sep.
4. Marshall M, Watt FE, Vincent TL, et al. Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management. Nat Rev Rheumatol. 2018 Nov;14(11): 641-656. doi: 10.1038/s41584-018-0095-4.
5. Zhang W, Doherty M, Leeb BF, et al. EULAR evidence based recommendations for the diagnosis of hand osteoarthritis: report of a task force of ESCISIT. Ann Rheum Dis. 2009 Jan;68(1):8-17. doi: 10.1136/ard.2007.084772. Epub 2008 Feb 4.
6. Plotz B, Bomfim F, Sohail MA, et al. Current epidemiology and risk factors for the development of hand osteoarthritis. Curr Rheumatol Rep. 2021 Jul 3;23(8):61. doi: 10.1007/s11926-021-01025-7.
7. Sowers M, Lachance L, Hochberg M, et al. Radiographically defined osteoarthritis of the hand and knee in young and middle aged African American and Caucasian women. Osteoarthritis Cartilage. 2000 Mar;8(2):69-77. doi: 10.1053/joca.1999.0273.
8. Kodama R, Muraki S, Oka H, et al. Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: The third survey of the ROAD study. Mod Rheumatol. 2016 Sep;26(5):767-73. doi: 10.3109/14397595.2015.1130673. Epub 2016 Feb 16.
9. Andrianakos AA, Kontelis LK, Karamitsos DG, et al. Prevalence of symptomatic knee, hand, and hip osteoarthritis in Greece: The ESORDIG study. J Rheumatol. 2006 Dec;33(12):2507-13.
10. Zhang Y, Niu J, Kelly-Hayes M, et al. Prevalence of symptomatic hand osteoarthritis and its impact on functional status among the elderly: The Framingham Study. Am J Epidemiol. 2002 Dec 1;156(11):1021-7. doi: 10.1093/aje/kwf141.
11. Zhang Y, Xu L, Nevitt MC, et al. Lower prevalence of hand osteoarthritis among Chinese subjects in Beijing compared with white subjects in the United States: The Beijing Osteoarthritis Study. Arthritis Rheum. 2003 Apr;48(4):1034-40. doi: 10.1002/art.10928.
12. Kalichman L, Kobyliansky E. Hand osteoarthritis in Chuvashian population: Prevalence and determinants. Rheumatol Int. 2009 Nov;30(1):85-92. doi: 10.1007/s00296-009-0920-9.
13. Kalichman L, Li L, Batsevich V, et al. Prevalence, pattern and determinants of radiographic hand osteoarthritis in five Russian community based samples. Osteoarthritis Cartilage. 2010 Jun;18(6):803-9. doi: 10.1016/j.joca.2010.02.006. Epub 2010 Feb 19.
14. Haugen IK, Englund M, Aliabadi P, et al. Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study. Ann Rheum Dis. 2011 Sep;70(9):1581-6. doi: 10.1136/ard.2011.150078. Epub 2011 May 27.
15. Nelson AE, Renner JB, Schwartz TA, et al. Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: the Johnston County Osteoarthritis Project. Arthritis Rheum. 2011 Dec;63(12):3843-52. doi: 10.1002/art.30610.
16. Toba N, Sakai A, Aoyagi K, et al. Prevalence and involvement patterns of radiographic hand osteoarthritis in Japanese women: the Hizen Oshima Study. J Bone Miner Metab. 2006;24(4):344-8. doi: 10.1007/s00774-006-0693-0.
17. Cho HJ, Morey V, Kang JY, et al. Prevalence and risk factors of spine, shoulder, hand, hip, and knee osteoarthritis in community dwelling Koreans older than age 65 years. Clin Orthop Relat Res. 2015 Oct;473(10): 3307-14. doi: 10.1007/s11999-015-4450-3. Epub 2015 Jul 11.
18. Haugen IK, Magnusson K, Turkiewicz A, et al. The prevalence, incidence, and progression of hand osteoarthritis in relation to body mass index, smoking, and alcohol consumption. J Rheumatol. 2017 Sep;44(9):1402-1409. doi: 10.3899/jrheum.170026. Epub 2017 Jul 15.
19. Kwok WY, Kloppenburg M, Rosendaal FR, et al. Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritis. Ann Rheum Dis. 2011 Jul;70(7):1238-42. doi: 10.1136/ard.2010.143016. Epub 2011 Apr 6.
20. Paradowski PT, Lohmander LS, Englund M. Natural history of radiographic features of hand osteoarthritis over 10 years. Osteoarthritis Cartilage. 2010 Jul;18(7):917-22. doi: 10.1016/j.joca.2010.04.008. Epub 2010 Apr 22.
21. Macias-Hernandez SI, Zepeda-Borbon ER, Lara-Vazquez BI, et al. Prevalence of clinical and radiological osteoarthritis in knee, hip, and hand in an urban adult population of Mexico City. Reumatol Clin (Engl Ed). 2020 Mar-Apr;16(2 Pt 2):156-160. doi: 10.1016/j.reuma.2018.06.001. Epub 2018 Sep 5.
22. Dahaghin S, Bierma Zeinstra SMA, Ginai AZ, et al. Prevalence and pattern of radiographic hand osteoarthritis and association with pain and disability (the Rotterdam Study). Ann Rheum Dis. 2005 May;64(5):682-7. doi: 10.1136/ard.2004.023564. Epub 2004 Sep 16.
23. Mannoni A, Briganti MP, Di Bari M, et al. Epidemiological profile of symptomatic osteoarthritis in older adults: a populationbased study in Dicomano, Italy. Ann Rheum Dis. 2003 Jun;62(6):576-8. doi: 10.1136/ard.62.6.576.
24. Yesil H, Hepgüler S, Öztürk C, et al. Prevalence of symptomatic knee, hand and hip osteoarthritis among individuals ≥40 years: a study conducted in zmir City. Acta Orthop Traumatol Turc. 2013;47(4):231-5. doi: 10.3944/aott.2013.2731.
25. Carmona L, Ballina J, Gabriel R, et al. The burden of musculoskeletal diseases in the general population of Spain: results from a national survey. Ann Rheum Dis. 2001 Nov;60(11): 1040-5. doi: 10.1136/ard.60.11.1040.
26. Dillon CF, Hirsch R, Rasch EK, et al. Symptomatic hand osteoarthritis in the United States: prevalence and functional impairment estimates from the third U.S. National Health and Nutrition Examination Survey, 1991–1994. Am J Phys Med Rehabil. 2007 Jan;86(1):12-21. doi: 10.1097/phm.0b013e31802ba28e.
27. Hirsch R, Guralnik JM, Ling SM, et al. The patterns and prevalence of hand osteoarthritis in a population of disabled older women: the Women’s Health and Aging Study. Osteoarthritis Cartilage. 2000:8 Suppl A:S16-21. doi: 10.1053/joca.2000.0330.
28. Kwok WY, Kloppenburg M, Marshall M, et al. Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community dwelling adults: the Keele clinical assessment studies. Rheumatology (Oxford). 2013 Dec;52(12):2260-7. doi: 10.1093/rheumatology/ket267. Epub 2013 Sep 17.
29. Cavasin F, Punzi L, Ramonda R, et al. Prevalence of erosive osteoarthritis of the hand in a population from Venetian area. Reumatismo. 2004 Jan-Mar;56(1):46-50. doi: 10.4081/reumatismo.2004.46.
30. Ye J, Wang Y, Yang T, et al. Prevalence and joint involvement patterns of erosive and non-erosive hand osteoarthritis in the general population in China. Arthritis Rheumatol. 2024;76(suppl 9):1200.
31. Kudinsky DM, Smirnov AV, Alekseeva LI, et al. Radiographic diagnosis of erosive hand osteoarthritis. Nauchno prakticheskaya revmatologiya. 2019;57(6):662 7. (In Russ.).
32. Sellam J, Maheu E, Crema MD, et al. The DIGICOD cohort: a hospital based observational prospective cohort of patients with hand osteoarthritis – methodology and baseline characteristics of the population. Joint Bone Spine. 2021 Jul;88(4):105171. doi: 10.1016/j.jbspin.2021.105171. Epub 2021 Mar 6.
33. Kloppenburg M, Kwok WY. Hand osteoarthritis — a heterogeneous disorder. Nat Rev Rheumatol. 2011 Nov 22;8(1):22-31. doi: 10.1038/nrrheum.2011.170.
34. Yoshida S, Aoyagi K, Felson DT, et al. Comparison of the prevalence of radiographic osteoarthritis of the knee and hand between Japan and the United States. Arthritis Rheum. 2003 Jun;48(6):1484-92. doi: 10.1002/art.10947.
35. Pishgar F, Kwee RM, Haj Mirzaian A, et al. Association between race and radiographic, symptomatic, and clinical hand osteoarthritis: a propensity score-matched study using Osteoarthritis Initiative data. Arthritis Rheumatol. 2022 Mar;74(3):453-461. doi: 10.1002/art.41231. Epub 2022 Feb 2.
36. Snyder EA, Alvarez C, Golightly YM, et al. Incidence and progression of hand osteoarthritis in a large community based cohort: the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage. 2020 Apr; 28(4):446-452. doi: 10.1016/j.joca.2020.02.028. Epub 2020 Feb 19.
37. Jordan JM. An ongoing assessment of osteoarthritis in African Americans and Caucasians in North Carolina: the Johnston County Osteoarthritis Project. Trans Am Clin Climatol Assoc. 2015:126:77-86.
38. Prieto Alhambra D, Judge A, Javaid MK, et al. Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints. Ann Rheum Dis. 2014 Sep;73(9):1659-64. doi: 10.1136/annrheumdis-2013-203355. Epub 2013 Jun 6.
39. Watt FE. Hand osteoarthritis, menopause and menopausal hormone therapy. Maturitas. 2016 Jan:83:13-8. doi: 10.1016/j.maturitas. 2015.09.007. Epub 2015 Oct 1.
40. Zhai G, Huang J. Genetics of osteoarthritis. Best Pract Res Clin Rheumatol. 2024 Dec; 38(4):101972. doi:10.1016/j.berh.2024.101972. Epub 2024 Jul 8.
41. Jonsson H, Manolescu I, Stefansson SE, et al. The inheritance of hand osteoarthritis in Iceland. Arthritis Rheum. 2003 Feb;48(2): 391-5. doi: 10.1002/art.10785.
42. Stecher RM. Heberden’s nodes. Heredity in hypertrophic arthritis of the finger joints. Am J Med Sci. 1941;201(6):8010.
43. Stecher RM, Hersh AH. Heberden’s nodes: the mechanism of inheritance in hypertrophic arthritis of the fingers. J Clin Invest. 1944 Sep;23(5):699-704. doi: 10.1172/JCI101540.
44. Irlenbusch U, Schäller T. Investigations in generalized osteoarthritis. Part 1: genetic study of Heberden’s nodes. Osteoarthritis Cartilage. 2006 May;14(5):423-7. doi: 10.1016/j.joca.2005.11.016. Epub 2006 Jan 27.
45. Hirsch R, Lethbridge Cejku M, Hanson R, et al. Familial aggregation of osteoarthritis: data from the Baltimore Longitudinal Study on Aging. Arthritis Rheum. 1998 Jul;41(7):1227-32. doi: 10.1002/1529-0131 (199807)41:73.0.CO;2-N
46. Ishimori ML, Altman RD, Cohen MJ, et al. Heritability patterns in hand osteoarthritis: the role of osteophytes. Arthritis Res Ther. 2010;12(5):R180. doi: 10.1186/ar3144. Epub 2010 Sep 28.
47. Magnusson K, Turkiewicz A, Haugen IK, et al. The genetic contribution to hand osteoarthritis. Osteoarthritis Cartilage. 2022 Oct; 30(10):1385-1389. doi: 10.1016/j.joca.2022.06.011. Epub 2022 Jul 14.
48. Kazmers NH, Meeks HD, Novak KA, et al. Familial clustering of erosive hand osteoarthritis in a large statewide cohort. Arthritis Rheumatol. 2021 Mar;73(3):440-447. doi: 10.1002/art.41520. Epub 2021 Jan 29.
49. Yusuf E, Nelissen RG, Ioan-Facsinay A, et al. Association between weight or body mass index and hand osteoarthritis: a systematic review. Ann Rheum Dis. 2010 Apr;69(4):761-5. doi: 10.1136/ard.2008.106930. Epub 2009 May 31.
50. Rydberg M, Dahlin LB, Gottsäter A, et al. High body mass index is associated with increased risk for osteoarthritis of the first carpometacarpal joint during more than 30 years of follow up. RMD Open. 2020 Oct;6(3): e001368. doi: 10.1136/rmdopen-2020-001368.
51. Reyes C, Leyland KM, Peat G, et al. Association between overweight and obesity and risk of clinically diagnosed knee, hip, and hand osteoarthritis: a population based cohort study. Arthritis Rheumatol. 2016 Aug;68(8): 1869-75. doi: 10.1002/art.39707.
52. Jiang L, Xie X, Wang Y, et al. Body mass index and hand osteoarthritis susceptibility: an updated meta analysis. Int J Rheum Dis. 2016 Dec;19(12):1244-1254. doi: 10.1111/1756-185X.12895. Epub 2016 Nov 5.
53. Salis Z, Driban JB, McAlindon TE, et al. Association of weight loss and weight gain with structural defects and pain in hand osteoarthritis: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2024 May;76(5):652-663. doi: 10.1002/acr.25284. Epub 2024 Feb 5.
54. Funck Brentano T, Nethander M, Moverare-Skrtic S, et al. Causal factors for knee, hip, and hand osteoarthritis: a Mendelian randomization study in the UK Biobank. Arthritis Rheumatol. 2019 Oct;71(10): 1634-1641. doi: 10.1002/art.40928. Epub 2019 Aug 29.
55. Rossignol M, Leclerc A, Allaert FA, et al. Primary osteoarthritis of hip, knee, and hand in relation to occupational exposure. Occup Environ Med. 2005 Nov;62(11):772-7. doi: 10.1136/oem.2005.020057.
56. Hunter DJ, Zhang Y, Nevitt MC, et al. Chopstick arthropathy: the Beijing Osteoarthritis Study. Arthritis Rheum. 2004 May;50(5):1495-500. doi: 10.1002/art.20145.
57. Calvet J, Orellana C, Larrosa M, et al. High prevalence of cardiovascular co morbidities in patients with symptomatic knee or hand osteoarthritis. Scand J Rheumatol. 2016 Jan;45(1):41-44. doi: 10.3109/03009742.2015.1054875. Epub 2015 Aug 31.
58. Wang F, Shi L, Xue QY. Association of metabolic factors with symptomatic hand osteoarthritis in the Chinese Han population aged 40 years and above. Chin Med J (Engl). 2016 Oct 5;129(19):2301-7. doi: 10.4103/0366-6999.190660.
59. Addimanda O, Mancarella L, Dolzani P, et al. Clinical associations in patients with hand osteoarthritis. Scand J Rheumatol. 2012 Aug;41(4):310-3. doi: 10.3109/03009742.2012.656699. Epub 2012 Mar 29.
60. Koutroumpas A, Giannoukas A, Zintzaras E, et al. Erosive hand osteoarthritis is associated with subclinical atherosclerosis and endothelial dysfunction. Int J Biomed Sci. 2013;9(4):217 22.
61. Cemeroglu O, Aydin HI, Yasar ZS, et al. Hand and heart, hand in hand: is radiological hand osteoarthritis associated with atherosclerosis? Int J Rheum Dis. 2014 Mar;17(3): 299-303. doi: 10.1111/1756-185X.12251. Epub 2013 Dec 14.
62. Hoeven TA, Kavousi M, Clockaerts S, et al. Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study. Ann Rheum Dis. 2013 May; 72(5):646-51. doi: 10.1136/annrheumdis2011-201178. Epub 2012 May 6.
63. Jonsson H, Helgadottir GP, Aspelund T, et al. Hand osteoarthritis in older women is associated with carotid and coronary atherosclerosis: the AGES Reykjavik study. Ann Rheum Dis. 2009 Nov;68(11):1696-700. doi: 10.1136/ard.2008.096289. Epub 2008 Nov 25.
64. Courties A, Sellam J, Maheu E, et al. Coronary heart disease is associated with a worse clinical outcome of hand osteoarthritis: a cross sectional and longitudinal study. RMD Open. 2017 Feb 15;3(1):e000344. doi: 10.1136/rmdopen-2016-000344. eCollection 2017.
65. Haugen IK, Ramachandran VS, Misra D, et al. Hand osteoarthritis in relation to mortality and incidence of cardiovascular disease: data from the Framingham Heart Study. Ann Rheum Dis. 2015 Jan;74(1):74-81. doi: 10.1136/annrheumdis-2013-203789. Epub 2013 Sep 18.
66. Hsueh TY, Chen YP. The association between dyslipidemia and hand osteoarthritis: a systematic review and meta analysis. Clin Rheumatol. 2025 Apr;44(4):1439-1448. doi: 10.1007/s10067-025-07384-1. Epub 2025 Mar 6.
67. Dahaghin S, Bierma-Zeinstra SMA, Koes BW, et al. Do metabolic factors add to the effect of overweight on hand osteoarthritis? The Rotterdam Study. Ann Rheum Dis. 2007 Jul;66(7):916-20. doi: 10.1136/ard.2005.045724. Epub 2007 Feb 21.
68. Altman R, Alarcon G, Appelrouth D, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis Rheum. 1990 Nov;33(11):1601-10. doi: 10.1002/art.1780331101.
69. Haugen IK, Felson DT, Abhishek A, et al. 2023 EULAR classification criteria for hand osteoarthritis. Ann Rheum Dis. 2024 Oct 21; 83(11):1428-1435. doi: 10.1136/ard-2023-225073.
70. Haugen IK, Felson DT, Abhishek A, et al. Development of classification criteria for hand osteoarthritis: comparative analyses of persons with and without hand osteoarthritis. RMD Open. 2020 Jun;6(2):e001265. doi: 10.1136/rmdopen-2020-001265.
71. Haugen IK, Felson D, Abhishek A, et al. Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2). RMD Open. 2022 Feb; 8(1):e002024. doi: 10.1136/rmdopen-2021-002024.
72. Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis Rheumatol. 2020 Feb; 72(2):220-233. doi: 10.1002/art.41142. Epub 2020 Jan 6.
73. Kloppenburg M, Kroon FPB, Blanco FJ, et al. 2018 update of the EULAR recommendations for the management of hand osteoarthritis. Ann Rheum Dis. 2019 Jan;78(1):16- 24. doi: 10.1136/annrheumdis-2018-213826. Epub 2018 Aug 28.
74. Ariani A, Manara M, Fioravanti A, et al. The Italian Society for Rheumatology clinical practice guidelines for the diagnosis and management of knee, hip and hand osteoarthritis. Reumatismo. 2019 Sep 23;71(S1):5-21. doi: 10.4081/reumatismo.2019.1188.
75. Kjeken I, Bordvik DH, Osteras N, et al. Efficacy and safety of non pharmacological, pharmacological and surgical treatments for hand osteoarthritis in 2024: a systematic review. RMD Open. 2025 Jan 9;11(1):e004963. doi: 10.1136/rmdopen-2024-004963.
76. Wang Y, Jones G, Keen HI, et al. Methotrexate to treat hand osteoarthritis with synovitis (METHODS): an Australian, multisite, parallel group, double blind, randomized, placebo controlled trial. Lancet. 2023 Nov 11;402(10414):1764-1772. doi: 10.1016/S0140-6736(23)01572-6. Epub 2023 Oct 12.
77. Alekseeva LI, Lila AM, Taskina EA, et al. Clinical guidelines (project) for the diagnosis and treatment of primary osteoarthritis for primary care specialists. Terapiya. 2023;1(1): 7-22. (In Russ.).
78. Alekseeva LI, Sharapova EP, Taskina EA, et al. Multicenter double blind randomized placebo controlled trial of symptom and structure modifying effect of Alflutop in patients with knee osteoarthritis. Report 2 – evaluation of the structure modifying effect of the drug. Nauchno prakticheskaya revmatologiya. 2014;52(2):174 7. (In Russ.).
79. Alekseeva LI, Sharapova EP, Taskina EA, et al. Multicenter double blind randomized placebo controlled trial of the symptom and structure modifying effect of Alflutop in patients with knee osteoarthrosis. Report 1 – evaluation of symptom modifying effect of the drug. Nauchno prakticheskaya revmatologiya. 2013;51(5):532 8. (In Russ.).
80. Karateev AE. Bioactive concentrate from small sea fish: Evaluation of the efficacy and safety of the drug on the basis of the analysis of 37 clinical trials. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2020; 14(4):111-124. (In Russ.). doi: 10.14412/1996-7012-2020-4-111-124.
81. Taskina EA, Alekseeva LI, Kashevarova NG, Lila AM. Long-term multicenter observational study of the drug Alflutop in Russia: use in patients with knee osteoarthritis (report 4). Sovremennaya Revmatologiya = Modern Rheumatology Journal. 2024;18(4):80-88. (In Russ.). doi: 10.14412/1996-7012-2024-4-80-88.
82. Lila AM, Taskina EA, Alekseeva LI, Kashevarova NG. Multicenter Longitudinal Observational Study Pharmaceuticals Alflutop in Russia (message 2). Sovremennaya Revmatologiya = Modern Rheumatology Journal. 2023; 17(4):75-85. (In Russ.). doi: 10.14412/1996-7012-2023-4-75-85
Review
For citations:
Taskina EA, Lila AM, Kashevarova NG, Alexeeva LI, Khalmetova AR. Osteoarthritis of the hands: epidemiology, risk factors, and modern diagnostics. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2025;19(4):13-24. (In Russ.) https://doi.org/10.14412/1996-7012-2025-4-13-24